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For everyone living with MS · And everyone who loves them

MS changes lives. Together, we can change what comes next.

My brother lives with progressive MS. His experience is personal, but he is far from alone: 37,756 Australians and 3.1 million people worldwide live with MS. We are bringing people together to fund research for better lives today and a world without MS tomorrow.

How 4 days of fundraisingWhen 26 to 30 November 2026Where free online, from anywhere

48-hour music stream starts in

The music event

How the 48-hour music stream works

The music is the final two days of our four-day fundraiser for MS Australia. Musicians from around the world will join together for one continuous run of performances lasting 48 hours.

  1. Each musician performs a scheduled live set on their own Twitch channel.
  2. When one set ends, the audience is sent together to the next musician’s channel, where the music continues. Twitch calls this handover a “raid”.
  3. Repeating that handover creates what Twitch calls a “raid train”. Ours continues day and night for 48 hours, and you can join, listen and donate at any point.
Supported by

Behind the event

Why this matters

More than 37,000 Australians live with MS. Every one of them has a life bigger than the disease.

Multiple sclerosis is a chronic disease of the central nervous system. The immune system mistakenly attacks tissue in the brain, spinal cord and optic nerve. The symptoms depend on where that damage occurs, which is why MS can look different from one person to the next.

It can affect movement, sight, balance, sensation, thinking and energy. Some symptoms are visible; many are not. No two people experience MS in the same way, and the uncertainty reaches families, friends and carers too.

My brother spent seven years without a diagnosis. That history matters, but the story did not end when the disease finally had a name. Living with progressive MS means living with change, adapting when the disease changes the rules, and continuing to build a life around it.

Research can help people live better with MS now, develop better treatments, prevent the disease and bring us closer to a cure. That is where every donation to MS Australia goes.

Your support can go further

Our partners are adding their support to what the community raises, helping turn individual donations into a bigger contribution to MS research.

Backed by DrawingHub and Waterline. More partner announcements are coming.

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What your donation changes

Better lives now. A world without MS tomorrow.

Every dollar goes to MS Australia, funding and coordinating research shaped by the priorities of people affected by MS: better treatment and care, prevention, diagnosis and a cure.

Living better with MS

Backing research into better treatments, care and management of the symptoms that shape daily life, including mobility, thinking, fatigue, pain and vision.

Stopping MS for good

Funding research to prevent MS, stop its progression, repair the damage it causes and ultimately cure the disease.

Donations to MS Australia are tax deductible in Australia. This is an independent fundraising event held in support of MS Australia.

How we are raising it

One cause. Three ways to help.

The fundraiser builds across four days, bringing workplaces, partners and musicians together around the same goal.

Thu 26 Nov

Waterline Charity Day

Our partners at Waterline hold a fundraising day in their office to kick the week off.

Fri 27 Nov Coming soon

More to be announced

Another way to support the fundraiser is taking shape. We will share the details here when it is ready.

Sat 28 to Mon 30 Nov

48 hours of live music

The main event. Musicians play live online, one after another, right through the day and night for two days without a break.

Take part across four days

Four days of fundraising. One cause.

The fundraiser begins on Thursday with two days of partner activity, then continues into a 48-hour live music event from Saturday morning to Monday morning. You can donate throughout and watch the music online for free.

Give to MS research

Donate from anywhere during the four-day fundraiser. Every dollar goes to MS Australia, and partner support helps the community total go further.

Follow the lead-up

Waterline opens the fundraiser on Thursday, with another activity to be announced for Friday before the music begins.

Watch the 48-hour stream

Musicians play continuously from Saturday morning to Monday morning. Drop in for one song or stay longer on Twitch or YouTube.

The music schedule below automatically shows every performance in your own time zone.

Full line-up and times

The 48-hour schedule

Times show in your own time zone. The schedule updates on its own as performers are confirmed.

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For musicians

Want to play?

If you are a musician who streams and you would like to take an hour, we would love to have you.

Slots run for one hour and are by invitation, coordinated through RaidPal. Get in touch and we will send you an access code and a time that suits you.

Sign up to play on RaidPal